Liên kết ngoài Phenylalanin

Liên kết ngoài Phenylalanin

Phenylalanin tại ChemSynthesis

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20 loại axit amin sinh protein

Phân loại theo tính chất

Bão hòa	Axit amin mạch nhánh •(Valin •Isoleucin •Leucin) •Methionin •Alanin •Prolin •Glyxin
Thơm	Phenylalanin •Tyrosin •Tryptophan •Histidin
Phân cực, không mang điện	Asparagin •Glutamin •Serin •Threonin
Tích điện dương (pKa)	Lysin (≈10.8) •Arginin (≈12.5) •Histidin (≈6.1)
Tích điện âm (pKa)	Axit aspartic (≈3.9) •Axit glutamic (≈4.1) •Cystein (≈8.3) •Tyrosin (≈10.1)
Phân loại chung	Axit amin thiết yếu •Protein •Peptit •Mã di truyền

Phân loại khác

Axit amin thiết yếu •Axit amin sinh ceton •Axit amin sinh đường

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Chất trung gian chuyển hóa axit amin

lysine→	Saccharopine • Allysine • Axit α-aminoadipic • α-cetoadipate • Glutaryl-CoA • Glutaconyl-CoA • Crotonyl-CoA • β-Hydroxybutyryl-CoA
leucine→	Axit α-cetoisocaproic • Isovaleryl-CoA • 3-Methylcrotonyl-CoA • 3-Methylglutaconyl-CoA • HMG-CoA
tryptophan→alanine→	N'-Formylkynurenine • Kynurenine • Axit Anthranilic • 3-Hydroxykynurenine • Axit 3-Hydroxyanthranilic • 2-Amino-3-carboxymuconic semialdehyde • 2-Aminomuconic semialdehyde • Axit 2-Aminomuconic • Glutaryl-CoA

Đ→pyruvate→citrate

glycine→serine→	Axit 3-Phosphoglyceric • glycine→creatine: Glycocyamine • Phosphocreatine • Creatinine

Đ→glutamate→
α-cetoglutarate

histidine→	Axit Urocanic • Axit Imidazol-4-one-5-propionic • Axit Formiminoglutamic • Glutamate-1-semialdehyde
proline→	Axit 1-Pyrroline-5-carboxylic
arginine→	Ornithine • Putrescine • Agmatine
khác	cysteine+glutamate→glutathione: γ-Glutamylcysteine

Đ→propionyl-CoA→
succinyl-CoA

valine→	Axit α-Cetoisovaleric • Isobutyryl-CoA • Methacrylyl-CoA • 3-Hydroxyisobutyryl-CoA • Axit 3-Hydroxyisobutyric • Axit 2-Methyl-3-oxopropanoic
isoleucine→	Axit 2,3-Dihydroxy-3-methylpentanoic • 2-Methylbutyryl-CoA • Tiglyl-CoA • 2-Methylacetoacetyl-CoA
methionine→	tạo homocysteine: S-Adenosyl methionine • S-Adenosyl-L-homocysteine • Homocysteine • chuyển hóa thành cysteine: Cystathionine • Axit alpha-Cetobutyric+Cysteine
threonine→	Axit α-Cetobutyric
propionyl-CoA→	Methylmalonyl-CoA

phenylalanine→tyrosine→	Axit 4-Hydroxyphenylpyruvic • Axit Homogentisic • 4-Maleylacetoacetate

Đ→oxaloacetate

xem chu trình ure

Khác

Chuyển hóa cysteine	Axit Cysteine sulfinic

Bản mẫu:Thuốc giảm đau Bản mẫu:Thuốc chống trầm cảm

Liên quan

Phenylalanin Phenytoin Phenylephrine Phenylpropanolamine Phenylethanolamine Phenylacetone Phenylacetaldehyd Phenyl salicylate Phenyl acetat Phenylmercury(II) borat

Tài liệu tham khảo

WikiPedia: Phenylalanin http://redpoll.pharmacy.ualberta.ca/drugbank/cgi-b... http://www.chemsynthesis.com/base/chemical-structu... http://books.google.com/?id=7JM8AAAAIAAJ&pg=PA93 http://books.google.com/books?id=6uVYAAAAYAAJ&pg=P... http://chemapps.stolaf.edu/jmol/jmol.php?model=c1c... http://pubchem.ncbi.nlm.nih.gov/summary/summary.cg... //www.ncbi.nlm.nih.gov/pubmed/2568989 http://www.genome.ad.jp/dbget-bin/www_bget?cpd:D00... http://www.commonchemistry.org/ChemicalDetail.aspx... //dx.doi.org/10.1126%2Fscience.1139247